Don't forget that the Berserker Armor is not the only improvement that Guts will have this time around.
Against Evil, his Dragon Slayer must be way stronger since that time at Fiora's mansion, since he mowed down tons of Trolls, Ogres, apostles (Zodd's troops), and most importantly laid the finishing blow against the Sea God with it.
If the fight against Grunbeld (who must be weaker than Zodd, but is still top-tiers apostles wise) when Guts first donned the armor is any indication, our protagonist could now slice through Zodd's transformed form like butter, and keep going until he can't regenerate any more.
When Guts was "riding" him, Zodd seemed to take the threat of the DS seriously...
If the SK duel during the eclipse also is of any indication, Zodd (transformed) discards weapons and only fights with his (rather small, considering...) claws... and his horn(s);
he is insanely strong (easily breaking Wyald's back, tanking several attacks from Ganishka) and quick, but is far from impervious to swords.
Both Griffith and Guts (very strong and skilled, but young and still humans) slashed him pretty deep during their Golden Age tag attack.
So with improved armor and improved Dragon Slayer, my money is on
I wouldn't be surprised if Zodd's remaining (and still growing) horn will end up being cut by Guts, that would be fitting.
Zodd could potentially fly and escape if he feels things are getting too dangerous, but it's not in his character as Miura established it.
The only way I could see Zodd winning would be crushing Guts with his overwhelming strength, like putting him in a bear hug and apply maximum force until
is crushed. But Guts should be too nimble now to get caught in his grip... Long days and pleasant nights