This is a dumb topic, but what the heck...
My gil is on Cloud. Guts is just a regular guy, Cloud is a genetically-enhanced solider with magic powers. No contest. It's like pitting the Punisher against Thor, or Green Arrow against Martian Manhunter.
I'll chime in for Priest as well. Spaghetti Westerns and horror are like chocolate and peanut butter.
Westerns and sci-fi are also two great tastes that taste great together, so you'd do well to check out Trigun.
And finally - though it's a novel, not a manga - there's Vampire Hunter D, which...
As long as it delivers scares and splatter, and doesn't take itself too seriously, Doom could be fun. Beisdes, where else will you see Eomer of Rohan team up with the Scorpion King to fight evil? :P
Back on Silent Hill - I haven't played any of the games since a demo of the first one (too...
I guess even as a Universal movie, Serenity couldn't quite escape the Friday Night Sci-Fi Curse that befell it's TV predecessor and other genre shows on Fox. :judo:
The DVD will probably sell like gangbusters, though, hopefully enough to fund a few more adventures in the 'verse.
Personally, I was really disappointed with the Berserk dub. The dubbing in the first episode was embarrassing, and less than five minutes into the next ep I switched back to the Japanese track. The dub in the Dreamcast game was a bit cheesy, but at least most of the voices fit the characters...