Well, they've already been using different Wesker voice actors depending on the game, even ones released around the same time, or switching back and forth. They seem to have a different one depending on how ridiculous the game is supposed to be, at least that's my way of knowing. =)
For example, since Wesker's not supposed to be known as a villain and because they're also playing it straight in REmake, he has a different voice actor who uses a normal voice, it still sounds like Wesker, just not so over the top. In RE0 on the other hand, it's the more ridiculous and hammy Count Dracula style of Code Veronica we've come to get used to, which makes sense since it's the same voice actor. The differences are obvious right down to the dialogue, in REmake he's totally straightforward and cold, even after his reveal, he's more cold-blooded killer than "I vant to suck your blud!" villain, then in RE0, which takes place within the same 48 hours, he's back to smugly spouting silly nonsensical diatribes about Umbrella, conspiracies, and more blah blah with William Birkin, the two of them awkwardly hanging out and rapping about the events of the day like friends after school.
Ugh, this fuckin' series! I liked it better when the cheesy B movie quality was unintentional and natural rather than forced, going back to my Leon bitterness.
